One of the often assumed correlations is between being cold and being sterile. When we think of a cold room the automatic assumption is that it is also clean and sterile. So what happens when this goes wrong?
Here is a PDF which looks at the problems when you get biological contamination.
The solution ? Hydrogen peroxied gas to kill all the germs! This is a very toxic substance and calls to mind some of the poison gases used during WW1. So not to be done lightly but it does seem to have worked.